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Panthenol
Panthenol
SoothingProvitamin B5 that hydrates, soothes, and supports skin repair.Benefits
Hydration and soothing
Supports repair
Reduces irritationSafe during pregnancy: Safe Safe for sensitive skin: SafeDaily use
View ingredient details -
Allantoin
Allantoin
SoothingA soothing and repairing ingredient that calms the skin and improves softness.Benefits
Soothing and repair
Skin softeningSafe during pregnancy: Safe Safe for sensitive skin: SafeDaily use
View ingredient details -
Retinol
Retinol
RetinoidA vitamin A derivative that speeds cell turnover and stimulates collagen.Benefits
Reduces wrinkles and fine lines
Improves texture and tone
Treats acne and marksSafe during pregnancy: Unsafe Safe for sensitive skin: Gradual☀ May increase sun sensitivity
Evening (PM) only
Cautions
Not for use during pregnancy or breastfeeding. Start gradually at night with daytime sunscreen.View ingredient details -
Hyaluronic Acid
Sodium Hyaluronate
HydratorA hydrating molecule that attracts and holds water in the skin for plumpness and radiance.Benefits
Deep hydration
Reduces the look of fine lines
Suitable for all skin typesSafe for sensitive skin: SafeDaily use
View ingredient details -
Ceramides
Ceramide NP
Skin barrier supportNatural lipids that form the skin barrier and help prevent water loss.Benefits
Repairs the skin barrier
Hydration and protection
Soothes dry skinSafe during pregnancy: Safe Safe for sensitive skin: SafeDaily use
View ingredient details -
PDRN / Salmon DNA
Sodium DNA
RepairA trending repair ingredient that renews skin and improves elasticity and texture.Benefits
Renewal and repair
Improves elasticity
RadianceSafe during pregnancy: Safe Safe for sensitive skin: SafeDaily use
Cautions
Limited pregnancy data; use with caution.View ingredient details
Full Ingredient List
Aqua, Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl p-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, PVM/MA Copolymer, Beta-Carotene, Sodium DNA
Product Description
Description:
Mary&May Spicule Retinol PDRN Cream is an advanced nighttime cream that combines natural marine micro-spicules (1/40th the size of a pore), nano-liposomal retinol, and soothing panthenol to improve the appearance of wrinkles, pores, and skin texture. It also contains Cica PDRN to support skin regeneration and strengthen collagen.
It is supported by ceramides, hyaluronic acid, and allantoin to strengthen the skin barrier and maintain hydration despite the potent retinal in the formula.
How to use:
- Take an appropriate amount and spread it evenly on the face, allowing it to absorb.
- Start with gradual use if your skin is trying retinol for the first time.
- Test on a small area of skin before first use.


















































